EB2 pS222 antibody
Por um escritor misterioso
Descrição
EB2 S222 site is a target for phosphorylation by the CDKL5 protein kinase; loss-of-function mutations in the human CDKL5 gene are associated with CDKL5 Deficiency Disorder, a neurodevelopmental disorder with intractable epilepsy (Baltussen, Negraes, et al
Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics. - Abstract - Europe PMC
Litterature
Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics. - Abstract - Europe PMC
Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability
Litterature
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology
Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics
Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics
Active human full-length CDKL5 produced in the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125, Microbial Cell Factories
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