A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia - ScienceDirect
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Descrição
Inhibition of the Menin (MEN1) and MLL (MLL1, KMT2A) interaction is a potential therapeutic strategy for MLL-rearranged (MLL-r) leukemia. Structure-ba…
Co-inhibition of HDAC and MLL-menin interaction targets MLL
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and
Therapeutic implications of menin inhibition in acute leukemias
Interaction modules that impart specificity to disordered protein
Synergistic targeting of FLT3 mutations in AML via combined menin
Designed to kill: novel menin-MLL inhibitors target MLL-rearranged
Frontiers Pharmacologic Targeting of Chromatin Modulators As
Menin-MLL inhibitors reverse oncogenic activity of MLL fusion
Outcomes of acute lymphoblastic leukemia with KMT2A (MLL
Menin-MLL inhibitors reverse oncogenic activity of MLL fusion
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